{"product_id":"protect-10-60ct","title":"Protect+ 10 (60ct)","description":"\u003cp data-start=\"618\" data-end=\"702\"\u003e\u003cstrong data-start=\"621\" data-end=\"702\"\u003eProtect+10 — Comprehensive Fat-Soluble Vitamin and Nutrient Absorption Support\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-start=\"704\" data-end=\"766\"\u003e\u003cstrong data-start=\"708\" data-end=\"766\"\u003eBalanced Protection for Bone, Heart, and Immune Health\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" data-sourcepos=\"27:1-27:84;843-926\"\u003eThe same fat-soluble vitamin synergy as Protect+ 5 — at twice the Vitamin D3 dose.*\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" data-sourcepos=\"29:1-29:407;928-1334\"\u003eProtect+ 10 delivers the identical K2VITAL® Delta, Vitamin A, Vitamin E, and AstraGin® foundation as Protect+ 5, with Vitamin D3 at 10,000 IU (250 mcg) — the therapeutic dose tier appropriate for patients with documented vitamin D insufficiency or deficiency, significant fat malabsorption, obesity, dark skin tone, advanced age, or those requiring accelerated D3 repletion under practitioner supervision.*\u003c\/p\u003e\n\u003cp class=\"font-claude-response-body break-words whitespace-normal\" data-sourcepos=\"31:1-31:418;1336-1753\"\u003eThe K2 co-administration at 300 mcg is clinically essential at this D3 dose. Higher D3 drives more robust calcium absorption — making the K2-mediated calcium direction mechanism even more important to ensure that mobilized calcium flows into bone matrix rather than vascular tissue.\u003cem\u003e\u003cspan\u003e \u003c\/span\u003eAt 10,000 IU D3, K2VITAL® Delta is not optional — it is the safety and efficacy partner that makes this dose clinically appropriate.\u003c\/em\u003e\u003c\/p\u003e\n\u003cp data-sourcepos=\"37:1-37:26;1982-2007\" class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003e\u003cstrong\u003eKEY SUPPORTED BENEFITS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-sourcepos=\"39:1-39:39;2009-2047\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eProtect+ 10 is formulated to support:*\u003c\/p\u003e\n\u003cul data-sourcepos=\"41:1-48:72;2049-2648\" class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli data-sourcepos=\"41:1-41:94;2049-2142\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eTherapeutic D3 repletion toward target serum 25(OH)D3 levels under practitioner monitoring*\u003c\/li\u003e\n\u003cli data-sourcepos=\"42:1-42:101;2143-2243\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eHealthy calcium metabolism — directing calcium to bone and away from soft tissues and vasculature*\u003c\/li\u003e\n\u003cli data-sourcepos=\"43:1-43:68;2244-2311\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eBone density, skeletal strength, and connective tissue integrity*\u003c\/li\u003e\n\u003cli data-sourcepos=\"44:1-44:67;2312-2378\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eVascular flexibility and healthy arterial calcification defense*\u003c\/li\u003e\n\u003cli data-sourcepos=\"45:1-45:72;2379-2450\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eImmune function, T-cell activity, and balanced inflammatory response*\u003c\/li\u003e\n\u003cli data-sourcepos=\"46:1-46:71;2451-2521\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eCell differentiation, tissue renewal, and mucosal barrier integrity*\u003c\/li\u003e\n\u003cli data-sourcepos=\"47:1-47:55;2522-2576\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eBroad-spectrum lipid-soluble antioxidant protection*\u003c\/li\u003e\n\u003cli data-sourcepos=\"48:1-48:72;2577-2648\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eFat-soluble vitamin absorption and bioavailability through AstraGin®*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-sourcepos=\"70:1-70:35;4267-4301\" class=\"text-text-100 mt-3 -mb-1 text-[1.125rem] font-bold\"\u003e\u003cstrong\u003eTHE FAT-SOLUBLE VITAMIN SYNERGY\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-sourcepos=\"72:1-72:41;4303-4343\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eWhy K2 at 10,000 IU D3 Is Non-Negotiable\u003c\/p\u003e\n\u003cp data-sourcepos=\"74:1-74:357;4345-4701\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eAt higher D3 doses, the calcium absorption-direction mechanism becomes more clinically important. 10,000 IU D3 drives robust intestinal calcium absorption — and without adequate K2 to activate osteocalcin and Matrix Gla Protein (MGP), a greater proportion of that calcium risks depositing in vascular smooth muscle and soft tissue rather than bone matrix.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"76:1-76:240;4703-4942\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eK2VITAL® Delta at 300 mcg provides the osteocalcin carboxylation and MGP activation that ensures absorbed calcium is directed appropriately at this D3 dose — making the D3\/K2 pairing in Protect+ 10 a clinical necessity, not a convenience.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"78:1-78:267;4944-5210\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eThe Vitamins A and E synergy is identical to Protect+ 5 — Vitamin A supports shared VDR\/RXR receptor signaling with D3 and mucosal immune function, while Vitamin E stabilizes the fat-soluble vitamin complex in lipoproteins and cell membranes throughout circulation.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"80:1-80:86;5212-5297\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eFor the full fat-soluble vitamin synergy rationale, see the Protect+ 5 product page.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"90:1-90:76;5489-5564\" class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003e\u003cstrong\u003eK2VITAL® Delta (Vitamin K2 as MK-7, Double Microencapsulated) — 300 mcg\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-sourcepos=\"91:1-92:63;5565-5705\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eRole: Calcium Direction, Bone Matrix Support \u0026amp; Vascular Calcification Defense- World's Only Patented Double-Microencapsulated K2\u003c\/p\u003e\n\u003cp data-sourcepos=\"94:1-94:269;5707-5975\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eK2VITAL® Delta delivers 99.7% all-trans MK-7 in the world's first and only patented double-microencapsulated preparation — with stability superiority confirmed across over 400 tests of finished products, achieving MK-7 recovery rates above 95% in mineral formulations.\u003c\/p\u003e\n\u003cp data-sourcepos=\"96:1-96:347;5977-6323\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eClinical Evidence: The 2024 Journal of the American College of Cardiology study demonstrated K2 MK-7 combined with D3 significantly impeded coronary artery calcification progression. The 2015 Knapen et al. RCT (Thrombosis and Haemostasis) showed 180 mcg MK-7 for 3 years significantly improved arterial stiffness in healthy postmenopausal women.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"96:1-96:347;5977-6323\" class=\"font-claude-response-body break-words whitespace-normal\"\u003e\u003cstrong\u003e\u003cspan\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0655\/5287\/5766\/files\/hydrovita-k2_480x480.jpg?v=1661869348\" alt=\"\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0655\/5287\/5766\/files\/Screen_Shot_2022-09-22_at_8.59.46_AM_480x480.png?v=1663851623\" alt=\"\"\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-sourcepos=\"102:1-102:55;6399-6453\" class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003e\u003cstrong\u003eVitamin D3 (Cholecalciferol) — 250 mcg (10,000 IU)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-sourcepos=\"103:1-103:96;6454-6549\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eRole: Therapeutic D3 Repletion, Calcium Absorption, Immune Gene Expression \u0026amp; Cellular Signaling\u003c\/p\u003e\n\u003cp data-sourcepos=\"105:1-105:260;6551-6810\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eAt 10,000 IU (250 mcg), Protect+ 10 delivers D3 at the therapeutic dose tier used by practitioners for accelerated repletion of documented vitamin D insufficiency and deficiency — and in clinical populations where 5,000 IU produces inadequate serum response.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"107:1-107:58;6812-6869\" class=\"font-claude-response-body break-words whitespace-normal\"\u003ePublished evidence for 10,000 IU D3 safety and efficacy:*\u003c\/p\u003e\n\u003cul data-sourcepos=\"108:1-111:170;6870-7728\" class=\"[li_\u0026amp;]:mb-0 [li_\u0026amp;]:mt-1 [li_\u0026amp;]:gap-1 [\u0026amp;:not(:last-child)_ul]:pb-1 [\u0026amp;:not(:last-child)_ol]:pb-1 list-disc flex flex-col gap-1 pl-8 mb-3\"\u003e\n\u003cli data-sourcepos=\"108:1-108:314;6870-7183\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eA comprehensive 2017 safety review in the Journal of Steroid Biochemistry and Molecular Biology (Hathcock et al.) established a no-observed-adverse-effect level (NOAEL) for Vitamin D3 at 10,000 IU\/day in healthy adults, with a tolerable upper intake level (UL) of 10,000 IU\/day — the dose used in this formula.*\u003c\/li\u003e\n\u003cli data-sourcepos=\"109:1-109:197;7184-7380\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eResearch demonstrates 10,000 IU\/day is frequently required to move deficient patients (below 20 ng\/mL) to the optimal range (40–80 ng\/mL) within a clinically meaningful timeframe of 2–4 months.*\u003c\/li\u003e\n\u003cli data-sourcepos=\"110:1-110:178;7381-7558\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003eA 2019 meta-analysis confirmed that supplemental D3 doses of 7,000–10,000 IU\/day are needed in many patient populations to consistently achieve serum 25(OH)D3 above 40 ng\/mL.*\u003c\/li\u003e\n\u003cli data-sourcepos=\"111:1-111:170;7559-7728\" class=\"font-claude-response-body whitespace-normal break-words pl-2\"\u003e10,000 IU D3 has been used safely in multiple published human studies examining immune function, autoimmune conditions, cancer prevention, and cardiometabolic health.*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-sourcepos=\"113:1-113:247;7730-7976\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eTarget serum levels: Most practitioners aim for 25(OH)D3 between 40–80 ng\/mL for optimal immune, bone, and cardiometabolic function. Regular monitoring every 3–6 months is recommended when supplementing at this dose to avoid exceeding 100 ng\/mL*\u003c\/p\u003e\n\u003cp data-sourcepos=\"127:1-127:24;9343-9366\" class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003e\u003cstrong\u003eVITAMIN A (RETINOL)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-sourcepos=\"128:1-129:74;9367-9474\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eDose: Clinically appropriate dose Role: Cell Differentiation, Mucosal Immunity, Tissue Renewal \u0026amp; D3 Synergy\u003c\/p\u003e\n\u003cp data-sourcepos=\"131:1-131:138;9476-9613\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eVitamin A (as retinol) is essential for a wide range of biological processes that are directly relevant to longevity and clinical health:\u003c\/p\u003e\n\u003cp data-sourcepos=\"133:1-133:291;9615-9905\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eCell differentiation and tissue renewal: Vitamin A regulates the differentiation of stem cells into specialized cell types across skin, respiratory epithelium, intestinal epithelium, and immune tissue — supporting the ongoing tissue renewal processes that maintain organ function with age.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"145:1-145:35;11091-11125\" class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003e\u003cstrong\u003eVITAMIN E (D-ALPHA TOCOPHEROL)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-sourcepos=\"146:1-147:96;11126-11255\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eDose: Clinically appropriate dose Role: Lipid-Soluble Antioxidant Defense, Membrane Integrity \u0026amp; Fat-Soluble Vitamin Stabilization\u003c\/p\u003e\n\u003cp data-sourcepos=\"149:1-149:246;11257-11502\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eVitamin E is the body's primary lipid-soluble chain-breaking antioxidant — integrated directly into cell membranes and lipoproteins where it interrupts lipid peroxidation chain reactions before they propagate through the membrane lipid bilayer.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"151:1-151:299;11504-11802\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eUnlike water-soluble antioxidants (vitamin C, glutathione) that protect the aqueous cellular compartments, Vitamin E specifically protects the lipid-rich environments that are the site of greatest oxidative vulnerability — cell membranes, mitochondrial membranes, myelin sheaths, and lipoproteins.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"165:1-165:74;12866-12939\" class=\"text-text-100 mt-2 -mb-1 text-base font-bold\"\u003e\u003cstrong\u003eASTRAGIN® (ASTRAGALUS MEMBRANACEUS + PANAX NOTOGINSENG ROOT EXTRACTS)\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-sourcepos=\"166:1-168:17;12940-13036\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eDose: 50 mg Role: Fat-Soluble Vitamin Absorption \u0026amp; Bioavailability Optimization \u003c\/p\u003e\n\u003cp data-sourcepos=\"170:1-170:148;13038-13185\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eAstraGin® upregulates key intestinal nutrient transporter proteins — supporting the absorption of fat-soluble vitamins across the intestinal wall.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"172:1-172:406;13187-13592\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eFat-soluble vitamins are absorbed through a lipid-dependent process involving bile acid micelles, pancreatic lipases, and specific intestinal transport proteins. AstraGin® supports the expression of these transport systems — including those involved in fat-soluble nutrient uptake — ensuring that the clinically validated forms of K2, D3, A, and E in Protect+ 5 are absorbed efficiently and consistently.*\u003c\/p\u003e\n\u003cp data-sourcepos=\"174:1-174:233;13594-13826\" class=\"font-claude-response-body break-words whitespace-normal\"\u003eAstraGin® also supports gut barrier integrity and healthy inflammatory tone in the intestinal environment — contributing to the absorptive surface health that determines fat-soluble vitamin bioavailability at the fundamental level.*\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eVitamin K2 MK-7:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eLal N, Berenjian A. Cis and trans isomers of the vitamin menaquinone-7: which one is biologically significant? Appl Microbiol Biotechnol. 2020 Apr;104(7):2765-2776. doi: 10.1007\/s00253-020-10409-1. Epub 2020 Feb 3. PMID: 32009201.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSato T, Inaba N, Yamashita T. MK-7 and Its Effects on Bone Quality and Strength. Nutrients. 2020 Mar 31;12(4):965. doi: 10.3390\/nu12040965. PMID: 32244313; PMCID: PMC7230802.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eKnapen MH, Braam LA, Drummen NE, Bekers O, Hoeks AP, Vermeer C. Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. A double-blind randomised clinical trial. Thromb Haemost. 2015 May;113(5):1135-44. doi: 10.1160\/TH14-08-0675. Epub 2015 Feb 19. PMID: 25694037.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eSimes DC, Viegas CSB, Araújo N, Marreiros C. Vitamin K as a Powerful Micronutrient in Aging and Age-Related Diseases: Pros and Cons from Clinical Studies. Int J Mol Sci. 2019 Aug 25;20(17):4150. doi: 10.3390\/ijms20174150. PMID: 31450694; PMCID: PMC6747195.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003ePisoschi AM, Pop A, Iordache F, Stanca L, Geicu OI, Bilteanu L, Serban AI. Antioxidant, anti-inflammatory and immunomodulatory roles of vitamins in COVID-19 therapy. Eur J Med Chem. 2022 Mar 15;232:114175. doi: 10.1016\/j.ejmech.2022.114175. Epub 2022 Feb 4. PMID: 35151223; PMCID: PMC8813210.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eVitamin D: \u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eChang SW, Lee HC. Vitamin D and health - The missing vitamin in humans. Pediatr Neonatol. 2019 Jun;60(3):237-244. doi: 10.1016\/j.pedneo.2019.04.007. Epub 2019 Apr 17. PMID: 31101452.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMartens PJ, Gysemans C, Verstuyf A, Mathieu AC. Vitamin D's Effect on Immune Function. Nutrients. 2020 Apr 28;12(5):1248. doi: 10.3390\/nu12051248. PMID: 32353972; PMCID: PMC7281985.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAo T, Kikuta J, Ishii M. The Effects of Vitamin D on Immune System and Inflammatory Diseases. Biomolecules. 2021 Nov 3;11(11):1624. doi: 10.3390\/biom11111624. PMID: 34827621; PMCID: PMC8615708.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eAbiri B, Vafa M. Vitamin D and Muscle Sarcopenia in Aging. Methods Mol Biol. 2020;2138:29-47. doi: 10.1007\/978-1-0716-0471-7_2. PMID: 32219739.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eVitamin A:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eBar-El Dadon S, Reifen R. Vitamin A and the epigenome. Crit Rev Food Sci Nutr. 2017 Jul 24;57(11):2404-2411. doi: 10.1080\/10408398.2015.1060940. PMID: 26565606.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eConaway HH, Henning P, Lerner UH. Vitamin a metabolism, action, and role in skeletal homeostasis. Endocr Rev. 2013 Dec;34(6):766-97. doi: 10.1210\/er.2012-1071. Epub 2013 May 29. PMID: 23720297.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eStephensen CB, Lietz G. Vitamin A in resistance to and recovery from infection: relevance to SARS-CoV2. Br J Nutr. 2021 Dec 14;126(11):1663-1672. doi: 10.1017\/S0007114521000246. Epub 2021 Jan 20. PMID: 33468263; PMCID: PMC7884725.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCantorna MT, Snyder L, Arora J. Vitamin A and vitamin D regulate the microbial complexity, barrier function, and the mucosal immune responses to ensure intestinal homeostasis. Crit Rev Biochem Mol Biol. 2019 Apr;54(2):184-192. doi: 10.1080\/10409238.2019.1611734. Epub 2019 May 14. PMID: 31084433; PMCID: PMC6629036.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eVitamin E: \u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003ePekmezci D. Vitamin E and immunity. Vitam Horm. 2011;86:179-215. doi: 10.1016\/B978-0-12-386960-9.00008-3. PMID: 21419272.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCasati M, Boccardi V, Ferri E, Bertagnoli L, Bastiani P, Ciccone S, Mansi M, Scamosci M, Rossi PD, Mecocci P, Arosio B. Vitamin E and Alzheimer's disease: the mediating role of cellular aging. Aging Clin Exp Res. 2020 Mar;32(3):459-464. doi: 10.1007\/s40520-019-01209-3. Epub 2019 May 3. PMID: 31054115.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eCorina A, Rangel-Zúñiga OA, Jiménez-Lucena R, Alcalá-Díaz JF, Quintana-Navarro G, Yubero-Serrano EM, López-Moreno J, Delgado-Lista J, Tinahones F, Ordovás JM, López-Miranda J, Pérez-Martínez P. Low Intake of Vitamin E Accelerates Cellular Aging in Patients With Established Cardiovascular Disease: The CORDIOPREV Study. J Gerontol A Biol Sci Med Sci. 2019 May 16;74(6):770-777. doi: 10.1093\/gerona\/gly195. PMID: 30165472.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eMoriguchi S, Muraga M. Vitamin E and immunity. Vitam Horm. 2000;59:305-36. doi: 10.1016\/s0083-6729(00)59011-6. PMID: 10714244.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan\u003eAstraGin®\u003c\/span\u003e\u003cspan\u003e:\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cspan\u003eChang, Tsu-Chung et al. “Effect of ginsenosides on glucose uptake in human Caco-2 cells is mediated through altered Na+\/glucose cotransporter 1 expression.” \u003c\/span\u003e\u003ci\u003e\u003cspan\u003eJournal of agricultural and food chemistry\u003c\/span\u003e\u003c\/i\u003e\u003cspan\u003e vol. 55,5 (2007): 1993-8. doi:10.1021\/jf062714k\u003c\/span\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cspan\u003eDuring A, Harrison EH. Mechanisms of provitamin A (carotenoid) and vitamin A (retinol) transport into and out of intestinal Caco-2 cells. J Lipid Res. 2007 Oct;48(10):2283-94. doi: 10.1194\/jlr.M700263-JLR200. Epub 2007 Jul 20. PMID: 17644776.\u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eReboul E, Goncalves A, Comera C, Bott R, Nowicki M, Landrier JF, Jourdheuil-Rahmani D, Dufour C, Collet X, Borel P. Vitamin D intestinal absorption is not a simple passive diffusion: evidence for involvement of cholesterol transporters. Mol Nutr Food Res. 2011 May;55(5):691-702. doi: \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan\u003eReboul E. Vitamin E intestinal absorption: Regulation of membrane transport across the enterocyte. IUBMB Life. 2019 Apr;71(4):416-423. doi: 10.1002\/iub.1955. Epub 2018 Oct 11. PMID: 30308094.\u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eCaution:\u003cspan\u003e \u003c\/span\u003e\u003c\/b\u003e\u003cspan\u003eIndividuals taking more than 50 mcg (2,000 IU) of Vitamin D per day should have their vitamin D levels monitored. This product is not intended for long term use and should be used under the supervision of your doctor. \u003c\/span\u003e\u003c\/p\u003e","brand":"Palomino IFM","offers":[{"title":"Default Title","offer_id":45960120434722,"sku":null,"price":49.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0798\/6223\/5170\/files\/Protect_10bottles.webp?v=1783632130","url":"https:\/\/palominoifmshop.myshopify.com\/products\/protect-10-60ct","provider":"palominoifmshop","version":"1.0","type":"link"}